Can NMN truly reverse age-associated physiological decline?
Dr Kathryn Mills
Old mice given NMN became as fit and strong as young mice. Their muscles and bones became stronger, had better energy production and improved endurance.
Mice treated with NMN also had stronger muscles and bones. Interestingly, the 513 genes that cause loss of muscle and bone density with aging were all suppressed with NMN in the study.
Treatment of mice with the NAD+booster nicotinamide mononucleotide (NMN) improves bloodflow and increases endurance in elderly mice by promoting SIRT1-dependent increases in capillary density.
NMN was able to mitigate most age-associated physiological declines in mice. The cells of old mice were indistinguishable from young mice after just one week of treatment.
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