NMN (Nicotinamide mononucleotide) supplementation promotes neurovascular rejuvenation in aged mice

Recent studies provide critical evidence that vascular aging is characterized by NAD+ depletion. There is increasing evidence showing that a decrease in NAD + availability with age plays a critical role in age-related neurovascular and cerebromicrovascular dysfunction. ¬†Our recent studies demonstrate that restoring cellular NAD+ levels in aged mice rescues neurovascular function, increases cerebral blood …

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