Reference: https://pubmed.ncbi.nlm.nih.gov/39811295/
A recent review article published in Heliyon examines the potential benefits of apigenin, a natural compound found in many fruits and vegetables, in combating atherosclerosis—a condition characterised by the buildup of fatty deposits in the arteries, leading to heart disease.
Apigenin is a type of flavonoid, which are plant-based compounds known for their health-promoting properties. This review highlights several ways apigenin may help prevent or treat atherosclerosis.
One key benefit of apigenin is its antioxidant effect. Antioxidants protect the body’s cells from damage caused by free radicals—unstable molecules that can harm cells and contribute to disease. By neutralizing these free radicals, apigenin may help prevent the oxidative stress that plays a significant role in the development of atherosclerosis.
Inflammation is another critical factor in atherosclerosis. The review points out that apigenin has anti-inflammatory properties, which may reduce inflammation in the arteries and slow the progression of the disease.
Additionally, apigenin may help regulate blood pressure. High blood pressure can damage artery walls, making them more susceptible to atherosclerosis. By helping to lower blood pressure, apigenin could contribute to healthier arteries.
The compound also appears to influence lipid metabolism—the way the body processes fats. Proper lipid metabolism is essential for maintaining healthy cholesterol levels, and apigenin may help balance these levels, reducing the risk of fatty deposits forming in the arteries.
In summary, the review suggests that apigenin holds promise as a natural agent against atherosclerosis due to its antioxidant, anti-inflammatory, blood pressure-regulating, and lipid-balancing effects. However, more research, including human studies, is needed to fully understand its potential benefits and applications in heart health.
