Nicotinamide mononucleotide (NMN) has been shown as safe in the short-term (up to six weeks); however, longer-term studies are required to prove safety. Article first appears in NMN.com Highlights At doses up to 1200 mg per day over a six-week time course, nicotinamide mononucleotide (NMN) supplementation has proven physiologically safe in humans. Currently, three FDA-regulated […]
In potential breakthrough research, experts are measuring cell and tissue decline to better understand how we age and to make better aging therapeutics. Published by Brett J. Weiss 2 April 2021 https://www.nmn.com/new1s/what-is-biological-aging How do we define aging? Historically, we’ve counted the number of times we live while the Earth orbits the sun (chronological […]
Researchers fight off childhood neurodegenerative disease characteristics rooted in NAD+ deficiency, mitochondrial damage, and senescence Published by Jonathan D. Grinstein, Ph.D. 12 April 2021 https://www.nmn.com/news/nad-boosting-protects-human-cells-from-premature-aging-disease Highlights · Mitochondrial dysfunction drives premature aging seen in ataxia telangiectasia (A-T). · Enhancing mitochondrial recycling by boosting NAD+ is a potential […]
Increasing production of SIRT6 extends lifespan by about 20%, improves physical activity, and mitigates frailty in old age. Published by By Brett J. Weiss 8 June 2021. https://www.nmn.com/news/researchers-substantially-extend-mouse-lifespan-by-activating-nad-dependent-and-energy-balancing-enzyme. Highlights · Mice genetically modified to overproduce SIRT6 protein see drastic increases in lifespan and physical performance. · SIRT6 improves […]
For the first time, a clinical study in older men shows that taking NMN increases blood NAD+ levels and improves various indicators of muscle strength and performance. This is an article published on https://www.nmn.com/news/12-weeks-of-nmn-supplementation-improves-muscle-function. By Brett J. Weiss 18 June 2021. Highlights NMN raises blood NAD+ and NAD+ metabolite levels in men over 65. Supplementing […]
https://www.sciencedirect.com/science/article/pii/S221323172030094X Published: July 2020 Abstract Age-related macular degeneration (AMD) is the leading cause of blindness among the elderly. Currently, there are no treatments for dry AMD, which is characterized by the death of retinal pigment epithelium (RPE) and photoreceptors. Reports from human donors with AMD suggest that RPE mitochondrial defects are a key event in […]
