NMN prevents chemo-induced mitochondrial defects, such as DNA damage and low cellular energy in neurons derived from human stem cells, a step forward in treating chemo-induced cognitive impairment. By Victor Ciardha Source: https://www.nmn.com/news/mayo-clinic-scientists-find-nmn-protects-against-chemo-induced-mitochondrial-dysfunction-in-human-neurons Highlights: “Chemobrain” is a term used to describe chemotherapy-induced cognitive impairment, which includes impaired memory, attention, and information processing. Up to 60% ... Read more
A new study has revealed that restoring NAD+ levels in the aging brain may be possible through the use of nicotinamide mononucleotide (NMN) or small vesicles containing the NAD+ synthesizing enzyme NAMPT (eNampt). The research, conducted by scientists at Washington University, showed that treating aged mice with NMN or eNampt led to increased NAD+ levels ... Read more
Brazilian scientists show that resveratrol reduces markers of inflammation and senescence (functional deterioration) in brain cells taken from aged rats. By Victor Ciardha Original Article: www.nmn.com Highlights: The hypothalamus controls everything from our reproductive success to our sleep-wake cycles. Scientists hypothesize that when this region of the brain becomes inflamed, our body is knocked out ... Read more
As an antioxidant promoter, NMN decreases lung damage in a mouse model of silicosis — an inflammatory lung disease caused by long-term inhalation of silica dust particles. From left to right: normal, silica-injured, and NMN-treated silica-injured lung tissue stained for scarring (purple). By Bella Richman Source: https://www.nmn.com/news/scientists-find-nmn-counters-lung-damage-caused-by-dust-inhalation Highlights: Aging is often associated with an increased ... Read more
Jilin University researchers show that nicotinamide mononucleotide (NMN) reduces stem cell senescence (aging) and restores mitochondrial function in rats by increasing the activity of sirtuin 3 (Sirt3) — a longevity-associated protein. Protein Data Bank Image of Sirtuin3 By Vanni Alagona Published: 4:41 p.m. PST Jan 10, 2023 | Updated: 5:37 p.m. PST Jan 10, 2023 ... Read more
The senolytic fisetin increases the muscle size and strength of prematurely aged mice by increasing muscle stem cells and reducing fat stem cells. Author, Dr. Paul D. Robbins | University of Minnesota By Victor Ciardha. www.nmn.com Highlights: The older we get, the weaker we tend to become, largely due to muscle atrophy (shrinkage) and ... Read more
