NMN prevents chemo-induced mitochondrial defects, such as DNA damage and low cellular energy in neurons derived from human stem cells, a step forward in treating chemo-induced cognitive impairment. By Victor Ciardha Source: https://www.nmn.com/news/mayo-clinic-scientists-find-nmn-protects-against-chemo-induced-mitochondrial-dysfunction-in-human-neurons Highlights: “Chemobrain” is a term used to describe chemotherapy-induced cognitive impairment, which includes impaired memory, attention, and information processing. Up to 60% […]
A new study has revealed that restoring NAD+ levels in the aging brain may be possible through the use of nicotinamide mononucleotide (NMN) or small vesicles containing the NAD+ synthesizing enzyme NAMPT (eNampt). The research, conducted by scientists at Washington University, showed that treating aged mice with NMN or eNampt led to increased NAD+ levels […]
Brazilian scientists show that resveratrol reduces markers of inflammation and senescence (functional deterioration) in brain cells taken from aged rats. By Victor Ciardha Original Article: www.nmn.com Highlights: The hypothalamus controls everything from our reproductive success to our sleep-wake cycles. Scientists hypothesize that when this region of the brain becomes inflamed, our body is knocked out […]
As an antioxidant promoter, NMN decreases lung damage in a mouse model of silicosis — an inflammatory lung disease caused by long-term inhalation of silica dust particles. From left to right: normal, silica-injured, and NMN-treated silica-injured lung tissue stained for scarring (purple). By Bella Richman Source: https://www.nmn.com/news/scientists-find-nmn-counters-lung-damage-caused-by-dust-inhalation Highlights: Aging is often associated with an increased […]
Jilin University researchers show that nicotinamide mononucleotide (NMN) reduces stem cell senescence (aging) and restores mitochondrial function in rats by increasing the activity of sirtuin 3 (Sirt3) — a longevity-associated protein. Protein Data Bank Image of Sirtuin3 By Vanni Alagona Published: 4:41 p.m. PST Jan 10, 2023 | Updated: 5:37 p.m. PST Jan 10, 2023 […]
The senolytic fisetin increases the muscle size and strength of prematurely aged mice by increasing muscle stem cells and reducing fat stem cells. Author, Dr. Paul D. Robbins | University of Minnesota By Victor Ciardha. www.nmn.com Highlights: The older we get, the weaker we tend to become, largely due to muscle atrophy (shrinkage) and […]