Chinese scientists find that boosting NAD+ with its precursor, NMN improves the learning and memory of a mouse model for Alzheimer’s disease. By Victor Ciardha Highlights: Treating Alzheimer’s disease (AD) mice with NMN improves their learning and memory. NMN restores energy metabolism, reduces inflammation, and eliminates beta-amyloid, a hallmark of AD. Inhibiting an enzyme that […]
A recently-published University of Toyama study from Japan reveals that a daily intake of 250 mg of nicotinamide mononucleotide (NMN) significantly raises blood NAD+. By Brett J. Weiss www.nmn.com Highlights Healthy human subjects who took two 125 mg doses of NMN per day for 12 weeks nearly doubled their whole blood nicotinamide adenine dinucleotide (NAD) […]
Nicotinamide mononucleotide (NMN)-treated antitumor CAR-T cells display enhanced effectiveness to combat cancer cells and reduce tumor growth in mice. By Brett J. Weiss www.nmn.com Highlights NMN treatment increases CAR-T cell — antitumor immune cell — proliferation up to 180 times, while prolonging the cells’ capabilities to kill cancer cells. With NMN treatment, anticancer CAR-T cells […]
Treating human cells with NMN triples NAD+ levels and increases the activity of AMPK — an enzyme that turns on sugar and fat metabolism in response to low energy. By Brett J. Weiss www.nmn.com Highlights Treating human breast cancer cells with NMN increases the activity of AMPK, a metabolic master switch that enhances cell energy […]
The anti-aging compounds NMN, metformin, and rapamycin prevent brain damage and alleviate memory deficiencies in a rat model for age-related cognitive impairment. By Brett J. Weiss www.nmn.com Highlights Treatment with NMN, metformin, or rapamycin improves learning and memory in rats modeling vascular cognitive impairment (VCI), the second leading cause of dementia after Alzheimer’s disease. […]
Chinese scientists find that NMN restores the age-related deterioration of the intestinal wall by boosting natural antioxidant defenses and reducing inflammation in older mice. By Victor Ciardha www.nmn.com Highlights: Increasing cellular NAD+ with NMN restores the structure of the intestinal wall in old mice, suggesting improved nutrient absorption. NMN increases the activation of genes associated […]